Anticholinergic effects

Cardiac arrhythmia due to medication

Certain drugs have the potential to adversely affect the repolarization of the heart and thereby cause cardiac arrhythmias of the “torsades de pointes” type. The risk can be increased by certain characteristics of the patient. These include, among other things, electrolyte disorders and certain previous diseases of the heart.

The RISK-PATH Score is a method to determine a patient’s risk of QT interval prolongation. The calculation is based on the publication by Vandael et al. A score greater than 10 indicates an increased risk for the patient. Measures should be taken to minimize risk factors that can be influenced.